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When to Speak to Your GP About Personality Changes Contact your GP or healthcare provider promptly if you experience any of the following whilst taking Mounjaro: Persistent low mood or depression lasting more than two weeks Significant anxiety that interferes with daily activities Unusual irritability or anger that is out of character for you Thoughts of self-harm or suicide – seek urgent help immediately via 999, A&E, your GP, NHS 111, or your local urgent mental health helpline Marked changes in sleep patterns (insomnia or excessive sleeping) Social withdrawal or loss of interest in previously enjoyed activities Concerning behavioural changes noticed by family members or friends If you experience sudden confusion, irritability or unusual behaviour and you are also taking insulin or sulfonylureas, check your blood glucose level as these symptoms could indicate hypoglycaemia requiring immediate treatment
