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In this study, a large portion of patients reported multiple discontinuation reasons, reflecting the multifaceted challenges involved in GLP-1 RA use — including tolerability, cost, access, and individual treatment goals
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Serious genitourinary infections, including urosepsis, pyelonephritis, and necrotizing fasciitis of the perineum (Fournier's gangrene, a rare life-threatening infection requiring urgent surgical intervention), have occurred in patients with and without diabetes mellitus receiving SGLT2 inhibitors, including empagliflozin [see Adverse Reactions (6.2)]
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